A Gangliocytic Paraganglioma Presenting as a Submucosal Tumor in the Ampulla.
- Author:
Jae Hoon YANG
1
;
Young Koog CHEON
;
Tae Yoon LEE
;
Chan Sup SHIM
;
Wook Youn KIM
Author Information
1. Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. 20110235@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Paraganglioma;
Gangliocytic;
Endoscopic mucosal resection
- MeSH:
Adult;
Biopsy;
Diagnosis;
Duodenitis;
Duodenum;
Endoscopy;
Female;
Ganglion Cysts;
Humans;
Mucous Membrane;
Neuroendocrine Tumors;
Paraganglioma*;
Ulcer
- From:Korean Journal of Medicine
2014;86(5):603-607
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A gangliocytic paraganglioma (GP) is a rare benign neuroendocrine tumor. However, its origin remains unclear. It is seen most frequently in the second portion of the duodenum. At endoscopy, a GP characteristically appears as a pedunculated nodular submucosal tumor with erosions and surface ulcers. The histological diagnosis is usually made from endoscopic biopsies showing the presence of epithelioid, spindle, and ganglion cells. We experienced a case of GP in a 38-year-old female who was referred because of a possible ampullary tumor. The endoscopic images showed a 1.5-cm, oval ampullary tumor covered with normal mucosa. An endoscopic biopsy showed chronic duodenitis. The tumor was removed by an endoscopic papillectomy. We report a case of duodenal GP that presented as a submucosal tumor that was treated with a papillectomy and review the literature.
