A Case of Infective Endocarditis with Cytomegalovirus Infection after Kidney Transplantation.
- Author:
Moon Ki HONG
1
;
Do Hyoung KIM
;
Chae Rim KIM
;
Joonhwa HONG
;
Mi Kyung KIM
;
Su Hyun KIM
Author Information
1. Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. sh76so@cau.ac.kr
- Publication Type:Case Report
- Keywords:
Aspergillus;
Cytomegalovirus;
Endocarditis;
Kidney transplantation
- MeSH:
Antifungal Agents;
Aspergillus;
Coinfection;
Cytomegalovirus;
Cytomegalovirus Infections*;
Endocarditis*;
Humans;
Immune System;
Kidney;
Kidney Transplantation*;
Korea;
Mitral Valve;
Risk Factors;
Superinfection;
Transplantation
- From:Korean Journal of Medicine
2014;86(5):627-631
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Advances in immunosuppressive therapy have increased the survival of kidney transplant recipients, yet suppression of the immune system after transplantation can promote infectious complications. Cytomegalovirus (CMV) infection remains one of the most important complications following kidney transplantation and it is a risk factor for developing superinfections with other organisms. Aspergillus endocarditis is a rare life-threatening complication in kidney transplantation. Coinfection of CMV and Aspergillus endocarditis is rare worldwide and has not been reported in Korea. We report a case of Aspergillus endocarditis that developed in a patient with CMV infection after kidney transplantation. His clinical condition did not improve despite mitral valve replacement and empirical antibiotic treatment, but he was eventually treated successfully with antifungal agents for 6 weeks.
