Effective Treatment of Intractable Diarrhea Associated with Common Variable Immunodeficiency with Oral Budesonide.
- Author:
Ji Hyun JEON
1
;
Do Hyoung LIM
;
Chang Hyun PARK
;
Hyeok Chan KWON
;
Ji Yeon JUNG
;
Keon Woo PARK
;
Soon Il LEE
Author Information
1. Department of Medicine, Dankook University College of Medicine, Cheonan, Korea. dos143@gmail.com
- Publication Type:Case Report
- Keywords:
Common variable immunodeficiency;
Diarrhea;
Steroid
- MeSH:
Adult;
Budesonide*;
Common Variable Immunodeficiency*;
Diarrhea*;
Humans;
Immunologic Deficiency Syndromes;
Male;
Prevalence;
Quality of Life
- From:Korean Journal of Medicine
2014;86(5):637-640
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency syndrome and has a high prevalence of gastrointestinal complications. We report the case of a 36-year-old male with CVID who presented with chronic intractable diarrhea and malabsorption. A comprehensive evaluation revealed no secondary causes of his symptoms. He was treated symptomatically without improvement. After receiving systemic steroid treatment, his symptoms improved, but returned soon after tapering the steroid. When he was subsequently administered oral budesonide, his symptoms and quality of life improved; this effect lasted for 20 months without unacceptable side effects.
