Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient.
- Author:
Hye Yun JEONG
1
;
San Ha KANG
;
Ji Hyun SONG
;
Sun Young SHIN
;
Daniel MIN
;
Kyu Hyun HAN
;
Jin Jung CHOI
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Bundang CHA Medical Center, CHA University, Seongnam, Korea. jinjungchoi@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Lupus erythematosus;
Systemic;
Antiphospholipid syndrome;
Splenic infarction
- MeSH:
Antibodies, Antiphospholipid;
Antiphospholipid Syndrome*;
Autoimmune Diseases;
Hemorrhage;
Humans;
Lupus Coagulation Inhibitor;
Lupus Erythematosus, Systemic*;
Prevalence;
Splenic Infarction*;
Splenic Rupture;
Thrombosis
- From:Korean Journal of Medicine
2014;86(5):651-654
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient.
