Clinical Analysis of Factors Influencing the Development of Delayed Ischemic Neurologic Deficit after Aneurysm Surgery.
- Author:
Chun Sik CHOI
1
;
Young Jun KWON
Author Information
1. Department of Neurosurery, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Delayed ischemic neurologic deficit;
Effect of surgery;
Temporary clipping
- MeSH:
Aneurysm*;
Brain;
Humans;
Logistic Models;
Neck;
Neurologic Manifestations*;
Odds Ratio
- From:Journal of Korean Neurosurgical Society
2002;31(3):241-246
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: This study shows the factors influencing the development of postoperative delayed ischemic neurologic deficit. METHODS: The authors analyzed 120 patients had performed aneurysmal neck clipping. Eleven variables were examined as to relationship to delayed ischemic neurologic deficit and classified as non- surgical and surgical variables. Data were analyzed by the univariate analysis and significant variables were entered into multiple logistic regression model in order to draw out Odds ratio. RESULTS: Delayed ischemic neurologic deficit after aneurysm surgery developed in 23 patients(19.2%). Significant non-surgical variables were clinical grade at admission(p=0.032), CT grade(p=0.005), and degree of preoperative angiographic vasospasm. Surgical variables were timing of surgery, brain retraction time, and duration of temporary clip application. The application time of temporary clip was significant (p=0.032) in development of delayed ischemic neurologic deficit. However, in multiple logistic regression analysis, duration of temporary clip application was excluded. With the clinical grade I - II and the CT grade I - II as the reference, the Odds ratio were 2.358(95% CI 0.87-6.37) and 4.041(95% CI 1.06-15.37), respectively. CONCLUSION: Delayed ischemic neurologic deficit after aneurysm surgery developed in poor clinical grade and high CT grade with high risk. The effect of surgery on the development of post-operative vasospasm was not significant.
