Kaposi's sarcoma occurring during short-term dialysis: report of two cases.
10.3346/jkms.2001.16.1.130
- Author:
Hwan HERR
1
;
Jeong Uk KIM
;
Gil Hyun KANG
;
Kee Chan MOON
;
Jai Kyoung KOH
Author Information
1. Department of Dermatology, Asan-Foundation Kangnung Hospital, Korea. herr@knh.co.kr
- Publication Type:Case Report
- Keywords:
Sarcoma, Kaposi's;
Dialysis;
Antigens, CD34;
Herpesvirus, Kaposi's Sarcoma-Associated
- MeSH:
Aged;
Case Report;
Herpesvirus, Kaposi Sarcoma-Associated/isolation & purification;
Human;
Kidney Transplantation/adverse effects;
Male;
Middle Age;
Renal Dialysis/adverse effects*;
Sarcoma, Kaposi/virology;
Sarcoma, Kaposi/therapy;
Sarcoma, Kaposi/etiology*
- From:Journal of Korean Medical Science
2001;16(1):130-134
- CountryRepublic of Korea
- Language:English
-
Abstract:
Kaposi's sarcoma (KS) appears to develop in association with kidney transplantation, but unlikely with dialysis. We report two cases of classic KS that occurred in patients receiving short-term (less than 3 yr) dialysis. They have been suffering from chronic renal failure due to tuberculosis and diabetes mellitus, respectively. Several to multiple, reddened-violaceous patches, plaques and nodules were found on the hand and the lower extremities. Laboratory studies showed no evidence suggesting immunosuppressed state and there was no history of taking immunosuppressive agents. The biopsies of the two cases revealed proliferation of spindle-shaped cells focally arranged in bundles and multiple dilated vascular spaces outlined by an attenuated endothelium with intravascular and extravasated erythrocytes. The specimens expressed positivity with CD34 antigen. Human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) was detected in one case by polymerase chain reaction method.
