T cell subsets of peripheral blood in patients with bladder cancer.
- Author:
Chang Kyu LEE
1
;
Jong Chul KIM
;
Hyun Yul RHEW
Author Information
1. Departmet of Urology, Kosin Medical College, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Bladder cancer;
Cellular immunity;
T cell subsets
- MeSH:
Antigens, Surface;
Humans;
Immunity, Cellular;
Pathology;
T-Lymphocyte Subsets*;
Urinary Bladder Neoplasms*;
Urinary Bladder*
- From:Korean Journal of Urology
1993;34(3):426-430
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently, to find a change of cellular immunologic function, the development of monoclonal anti-body for surface antigen of T cell subsets is used as an important method of quantitative and functional measure in T cell subsets. We evaluated the T cell subsets in the peripheral blood of 145 normal control group and 106 bladder cancer group which was diagnosed by tissue pathology during the period from June 1986 to June 1992. The results of this study showed that CD3 of T cell subsets was significantly decreased in bladder cancer group as compared with normal control group(p<0.05) and significantly decreased in T1 and T1 groups of bladder cancer groups(p<0.05). But CD4/CD8 ratio was not decreased in bladder cancer group as compared with normal control group.
