Disseminated Mycobacterium avium Complex Infection in a Non-HIV-infected Patient Undergoing Continuous Ambulatory Peritoneal Dialysis.
10.3343/kjlm.2010.30.2.166
- Author:
Jin Won CHUNG
1
;
Young Ju CHA
;
Dong Jin OH
;
Woo Jin NAM
;
Su Hyun KIM
;
Mi Kyung LEE
;
Hye Ryoun KIM
Author Information
1. Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. intmdoh@cau.ac.kr
- Publication Type:Case Report
- Keywords:
End-stage renal disease;
Mycobacterium avium complex;
Bone marrow
- MeSH:
Aged;
Anti-Bacterial Agents/therapeutic use;
Bacterial Proteins/genetics;
Bone Marrow/microbiology/pathology;
Diagnosis, Differential;
Female;
HIV Infections/diagnosis;
Humans;
Kidney Failure, Chronic/therapy;
*Mycobacterium avium Complex/genetics/isolation &purification;
Mycobacterium avium-intracellulare Infection/*diagnosis/drug therapy/microbiology;
*Peritoneal Dialysis, Continuous Ambulatory;
Polymerase Chain Reaction;
Polymorphism, Restriction Fragment Length;
Sequence Analysis, DNA
- From:The Korean Journal of Laboratory Medicine
2010;30(2):166-170
- CountryRepublic of Korea
- Language:English
-
Abstract:
Isolated bone marrow infection by nontuberculous mycobacteria (NTM) is extremely rare. Recently, we encountered a case of bone marrow Mycobacterium avium complex (MAC) infection, which presented as a fever of unknown origin shortly after starting continuous ambulatory peritoneal dialysis (CAPD). The patient was diagnosed with MAC infection on the basis of PCR-restriction fragment length polymorphism analysis and sequencing of DNA obtained from bone marrow specimens. Although this was a case of severe MAC infection, there was no evidence of infection of other organs. End-stage renal disease (ESRD) patients undergoing dialysis can be considered immunodeficient; therefore, when these patients present with fever of unknown origin, opportunistic infections such as NTM infection should be considered in the differential diagnosis.
