Hypereosinophilic Syndrome Accompanied by Digital Necrosis.
- Author:
Jae Cheol KIM
1
;
Sang Kuon LEE
;
Yong Gui KIM
;
In Sung MOON
;
Seung Nam KIM
;
Yong Bok KOH
Author Information
1. Department of Surgery, College of Medicine, The Catholic University of Korea.
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
Vasculitis;
Digital necrosis
- MeSH:
Adult;
Biopsy;
Bone Marrow;
Central Nervous System;
Eosinophilia;
Eosinophils;
Gastrointestinal Tract;
Heart;
Humans;
Hypereosinophilic Syndrome*;
Hyperplasia;
Liver;
Necrosis*;
Peripheral Nervous System Diseases;
Respiratory System;
Spleen;
Vasculitis
- From:Journal of the Korean Surgical Society
2000;58(5):740-744
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated dysfunctions of organ systems, including the hematologic, cardiovascular, cutaneous, neurologic and respiratory systems, as well as the spleen, liver, eye, and gastrointestinal tract. Bone marrow is involved in almost all subjects, and the most severe complications involve the heart and the central nervous systems. We report a case of HES observed in a 37-year-old man with digital necrosis and persistent eosinophilia lasting for more than 6 months. This patient also showed signs of peripheral neuropathy, cutaneous manifestations, and eosinophilic hyperplasia on the bone marrow biopsy.