Combined Pneumocystis Carinii Pneumonia and Miliary Tuberculosis in a Patient with AIDS.
- Author:
So Young PARK
;
Hye Kyung LEE
- Publication Type:Original Article
- Keywords:
Acquired immune deficiency syndrome(AIDS);
Pneumocystis carinii;
Tuberculosis
- MeSH:
Mortality;
Biopsy
- From:Korean Journal of Pathology
1994;28(6):657-662
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Patients with AIDS frequently present with pulmonary complications which are associated with a high mortality rate and infections are the most important cause of lung infiltrates. In addition to pneumonia caused by Pneumocystis carinii, which was noted in early reports of the syndrome, a variety of other severe pulmonary disorders may occur. Frequently more than one organism is found in a single patient and among these, combined infections of Pneumocystis carinii and cytomegalovirus are the most common. We experienced a case of combined Pneumosytis carinii and Mycobacterium tuberculosis infection as a pulmonary manifestation of AIDS in a 38-year-old man. In bronchoalveolar larvage, bronchial washing and brushing, and sputum smear specimens, Pneumocystis carinii organisms were recognized, especially in Gomori's methenamine silver stains. Transbronchial lung biopsy specimen revealed intra-alveolar frothy exudates composed of collections of Pneumocystis carinii organisms as well as several granulomas with central caseous necroses.