Changes In The Distribution of Oxytocin and Vasopressin-Immunoreactive Neurons In the Hypothalamic Area of Normal and Hypophysectomized Rats.
10.11637/kjpa.1999.12.1.33
- Author:
Young Gil JEONG
1
;
Nam Seob LEE
;
Chul Ho LEE
;
Byung Hwa HYUN
Author Information
1. Department of Anatomy, College of Medicine, Konyang University, Nonsan, Korea.
- Publication Type:Original Article
- Keywords:
Vasopressin;
Oxytocin;
Hypophysectomy;
Immunohistochemistry;
Rat
- MeSH:
Animals;
Hypophysectomy;
Hypothalamic Area, Lateral;
Immunohistochemistry;
Median Eminence;
Neurons*;
Oxytocin*;
Paraventricular Hypothalamic Nucleus;
Rats*;
Supraoptic Nucleus;
Vasopressins
- From:Korean Journal of Physical Anthropology
1999;12(1):33-44
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The localization and number of oxytocin- and vasopressin-immunoreactive neurons (OXY-IR & VP-IR) and their fibers in the hypothalamic areas (supraoptic nucleus, paraventricular nucleus, lateral hypothalamic area and median eminence) of the hypophysectomized rat were compared with normal rats at 6 months of survival after surgery at the light microscopic level. The number of VP-IR neurons was markedly decreased in the supraoptic nucleus (SON) and paraventricular nucleus (PVN) in the hypophysectomized rats as compared to normal rats. Moreover, The number of VP-IR fibers was decresed in the SON, PVN, lateral hypothalamic area (LHA) and median eminence in the hypophysectomized rats. The number of OXY-IR neurons and thier fibers were also decreased in the SON and PVN in the hypophysectomized rats. The present results demonstrate that hypophysectomy induces a significant decrease in the number of OXY- and VPIR neurons and fibers within hypothalamic areas (SON, PVN, and LHA at 6 months of post-hypophysectomy) are decreased.
