Antimicrobial drug resistance of gram negative bacilli isolated from urine.
- Author:
Byung Wook SEO
1
;
Young Bum CHA
;
Cheol Hee PARK
;
Sung Jun LEE
;
Woo Ki BAEK
;
Seong Il SUH
;
Min Ho SUH
Author Information
1. Department of Urology, Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Gram negative bacilli;
Quinolone;
Antimicrobial Resistance
- MeSH:
Amikacin;
Anti-Bacterial Agents;
Ciprofloxacin;
Drug Resistance, Microbial*;
Enoxacin;
Escherichia coli;
Humans;
Klebsiella;
Moxalactam;
Nalidixic Acid;
Norfloxacin;
Nose;
Ofloxacin;
Pefloxacin;
Proteus;
Pseudomonas aeruginosa;
Quinolones;
Rifampin;
Tetracycline;
Urologic Diseases
- From:Korean Journal of Urology
1991;32(2):264-273
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
One hundred and fifty strains of Gram negative bacilli isolated from urine of patients with urological disease were tested for resistance to antimicrobial drugs including quinolones. Escherichia coli (61 strains) was most frequently isolated, and followed by Klebsiella spp. (36), Pseudomonas aeruginosa (12). and Proteus spp. (6) in the decreasing order. New quinolone carboxylic acid compounds such as enoxacin (Ex). norfloxacin (Nf), ciprofloxacin (Cp), pefloxacin (Pf), and ofloxacin (Of) showed very high antimicrobial activities against the majority of organisms tested except P.aerogi. nose. In P.aeruginosa all strains were resistant to nalidixic acid, and 25-33% to Ex. Nf. Cp, Pf, and Or. The majority of strains tested were found to be resistant to beta-lactam antibiotics except moxalactam (Mr). aminoelycoside drugs except amikacin (Ak), and other drugs tested such as chloramphgnicol, tetracycline. rifampin and etc.. but in P.aeruginosa, 33-58% were resistant to Mx and Ak. Organisms multiplyine resistance to 5 or more druge were noted in almost all isolates tested The stain numbers of multiplying resistance to 5 or more drugs were 51 strains (83.6%) of E. Coli 24 strains (66.7%) of Klebsielle spp., 10 strains (83.3%) of P.aeruginosa, and 5 strains (83.3%) of Prorteus spp.
