Clinical Factors Affecting Postoperative Mortality in Necrotizing Enterocolitis.
- Author:
Hong Jae JO
1
;
Yong Hoon CHO
;
Hae Young KIM
Author Information
1. Department of Surgery, School of Medicine, Pusan National University, Busan, Korea. haeyoung@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Necrotizing enterocolitis;
Postoperative mortality;
Prognostic factor;
Extent of necrosis
- MeSH:
Busan;
Emergencies;
Enterocolitis, Necrotizing*;
Gestational Age;
Humans;
Infant;
Intestines;
Mortality*;
Parturition;
Retrospective Studies
- From:Journal of the Korean Surgical Society
2006;70(5):390-395
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Necrotizing enterocolitis (NEC) is one of the most common surgical emergencies during the neonatal period. The aim of this study was to identify and assess the factors affecting the postoperative mortality in infants with NEC that require surgical treatment. METHODS: The authors retrospectively reviewed 37 infants surgically treated, at the Department of Surgery, Pusan National University Hospital, between Jan. 2000 and Dec. 2004. The patients were divided two groups according to the clinical outcomes; the survival and non-survival groups. Eight variables, i.e., sex, gestational age, weight at birth and at the time of the first operation, weight change between birth and the time of the first operation, degree of clinical manifestations (as a modified Bell's stage), interval between the onset of symptoms and the time of the first operation, the extent of necrotic intestine and associated anomalies, were analyzed. RESULTS: Among 37 infants, 6 expired (a mortality rate of 16.2%). The postoperative mortality was not affected by sex, gestational age, and the weight at birth and at the time of the first operation, weight change between birth and at the time of the first operation, degree of clinical manifestations and the interval between the onset of symptoms and the time of the first operation. However, the extent of necrotic intestine was associated with a significantly increased mortality (P=0.046). CONCLUSION: These data suggest that the extent of necrotic intestine is the only statistically significant factor affecting the postoperative mortality in infants with NEC that require surgical treatment.
