A Case of Diffuse Large B Cell Lymphoma Transformed from a Duodenal Low Grade MALT Lymphoma.
- Author:
Soon Joo KIM
1
;
Gin Hyug LEE
;
Sang Hyun PARK
;
Hyun Deok SHIN
;
Chang Lae JO
;
Tae Hyup KIM
;
Ho June SONG
;
Kee Don CHOI
;
Hwoon Yong JUNG
;
Jin Ho KIM
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jhlee409@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Lymphoma;
Mucosa-associated lymphoid tissue;
Diffuse large B cell
- MeSH:
Aged;
Biopsy;
Drug Therapy, Combination;
Duodenum;
Endoscopy;
Female;
Humans;
Lymph Nodes;
Lymphocytes;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell*;
Lymphoma, B-Cell, Marginal Zone*
- From:Korean Journal of Gastrointestinal Endoscopy
2007;34(2):103-107
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Duodenal mucosa-associated lymphoid tissue (MALT) lymphoma is a very rare neoplasm. We report here a case of a 67-year-old woman with a diffuse large B cell lymphoma arising in a low grade MALT lymphoma in the duodenal bulb. She was asymptomatic and on a general health evaluation an upper endoscopy showed an extensive erosive lesion on the duodenal bulb. The biopsy specimen showed lymphocyte infiltration with lymphoepithelial lesions suggesting a low grade MALT lymphoma. A second upper endoscopy with biopsy discovered a focal diffuse large B cell lymphoma in the background of a low grade MALT lymphoma. A meticulous staging work-up revealed that the lymphoma was confined to the duodenum and regional lymph nodes. Finally, the patient was diagnosed as having a diffuse large B cell lymphoma transformed from a duodenal low grade MALT lymphoma. The patient was undergoing combination chemotherapy including the use of an anti-CD20 monoclonal antibody.
