MRI Findings of Long-term Survivals after Kasai Portoenterostomy.
10.13029/jkaps.2012.18.1.12
- Author:
Jikwang JUNG
1
;
Eunyoung JUNG
;
Woo Hyun PARK
;
Soon Ok CHOI
Author Information
1. Department of Pediatric Surgery, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. choi1635@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Biliary atresia;
Kasai operation;
MRI;
Macroregenerative nodule;
Beaded duct dilatation
- MeSH:
Biliary Atresia;
Bilirubin;
Cholangitis;
Dilatation;
Dioxoles;
Humans;
Liver;
Odds Ratio;
Survivors
- From:Journal of the Korean Association of Pediatric Surgeons
2012;18(1):12-17
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study is to analyse clinical impact of specific MRI findings in liver in patients of long-term survivors after Kasai portoenterostomy (KPE). Twenty-eight patients who were underwent KPE were followed up more than 5 years. Macro-regenerative nodule (MRN) and beaded-duct dilatation (BDD) were considered as important findings in liver MRI. The association between these findings in MRI and clinical indicator, serum bilirubin level and history of cholangitis were evaluated. Sixteen patients (57.1%) were shown MRN in liver MRI. There were 14 patients(50%) whose MRI showed BDD. Serum total and direct bilirubin were 3.6mg/dL and 1.8mg/dL respectively in positive MRN group whereas 1.4mg/dL and 0.7mg/dL in negative MRN group (p 0.427). Serum total and direct bilirubin level were 4.2mg/dL and 2.1mg/dL in patients with BDD negative group compare to 1.1mg/dL and 0.5mg/dL in BDD positive group (p 0.281). The odds ratio to have cholangitis in the patient with MRN was 2.3 and 0.53 in patient with BDD in their MRI findings. MRN in liver MRI may suggest high bilirubin level and more chance to have cholangitis, but the findings of BDD may related to low bilirubin level and less change to have cholangitis.
