Increased humoral antibody response of foot-and-mouth disease virus vaccine in growing pigs pre-treated with poly-γ-glutamic acid.
10.4142/jvs.2016.17.2.253
- Author:
Jee Hoon LEE
1
;
Ik Jae KANG
;
A Reum KIM
;
You Sun NOH
;
Hee Chun CHUNG
;
Bong Kyun PARK
Author Information
1. Department of Veterinary Medicine Virology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea. parkx026@snu.ac.kr
- Publication Type:Brief Communication
- Keywords:
foot-and-mouth disease virus vaccine;
humoral immune response;
poly-γ-glutamic acid
- MeSH:
Animals;
Antibody Formation*;
Enzyme-Linked Immunosorbent Assay;
Foot-and-Mouth Disease Virus*;
Foot-and-Mouth Disease*;
Immunity, Humoral;
O Antigens;
Serogroup;
Swine*;
Vaccination
- From:Journal of Veterinary Science
2016;17(2):253-256
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was conducted to determine if humoral antibody response of foot-and-mouth disease (FMD) vaccine improved in 8-week-old growing pigs born to well-vaccinated sows pre-treated with 60 mg of poly-γ-glutamic acid (γ-PGA) three days before vaccination. Antibody against FMD virus serotype O was measured 0, 2, 4 and 6 weeks post-vaccination, using a PrioCHECK FMDV type O ELISA kit. The results showed that positive antibody reactions against FMDV serotype O antigen among a component of the vaccine significantly increased in response to pre-injection with γ-PGA.
