Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
10.3346/jkms.2000.15.5.598
- Author:
Hyo Sung KWAK
1
;
Myoung Hee SOHN
;
Seok Tae LIM
;
Jae Yong KWAK
;
Chang Yeol YIM
Author Information
1. Department of Diagnostic Radiology, Chonbuk National University, Chonju, Korea.
- Publication Type:Case Report
- Keywords:
Leukemia, Myeloid, Chronic;
Hypercalcemia;
Radionuclide Imagin
- MeSH:
Adult;
Bone Diseases/radionuclide imaging*;
Bone Diseases/etiology*;
Calcinosis/radionuclide imaging;
Calcinosis/etiology;
Case Report;
Human;
Hypercalcemia/radionuclide imaging*;
Hypercalcemia/etiology*;
Leukemia, Myeloid, Chronic/metabolism;
Leukemia, Myeloid, Chronic/complications*;
Male;
Middle Age;
Proteins/metabolism;
Technetium/diagnostic use
- From:Journal of Korean Medical Science
2000;15(5):598-600
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach may occur. Our two cases were admitted because of severe hypercalcemia in accelerated phase of CML. On Tc-99m methylene diphosphonate (MDP) bone scintigraphies, a marked tracer accumulation was seen in the lung, heart, stomach and kidney. We report increased tracer accumulation of multiple organs on Tc-99m MDP bone scintigraphy in two rare hypercalcemic patients with CML.
