Two patients with acquired hemophilia successfully treated with combination therapy including therapeutic plasmapheresis.
- Author:
Eunkyung PARK
1
;
Joung Soon JANG
;
Seonyang PARK
;
Sang Jae LEE
Author Information
1. Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. lisa1114@naver.com
- Publication Type:Case Report
- Keywords:
Hemophilia A;
Factor VIII;
Autoantibodies;
Plasmapheresis
- MeSH:
Autoantibodies;
Factor VIII;
Female;
Hemophilia A;
Hemorrhage;
Humans;
Immunosuppressive Agents;
Plasmapheresis;
Purpura
- From:Korean Journal of Medicine
2009;77(3):367-370
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acquired hemophilia is a rare disorder associated with fatal bleeding caused by the development of autoantibodies against factor VIII. Here, we report the cases of two young women with acquired hemophilia who presented with massive internal hemorrhage and purpura. Both patients were successfully treated with combination therapy including factor VIII or factor VIII bypassing agent, immunosuppressants, and therapeutic plasmapheresis.
