Evaluation of Plasma Vitamin A and E Levels and Tear Film Changes in Patients with Psoriasis Vulgaris.
10.3341/kjo.2013.27.3.158
- Author:
Helin Deniz DEMIR
1
;
Erdinc AYDIN
;
Engin SEZER
;
Huseyin YARDIM
Author Information
1. Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. helindeniz@hotmail.com
- Publication Type:Original Article
- Keywords:
Ophthalmological diagnostic techniques;
Psoriasis;
Vitamin A;
Vitamin E
- MeSH:
Adolescent;
Adult;
Female;
Humans;
Male;
Middle Aged;
Mucins/*metabolism;
Psoriasis/*metabolism;
Tears/*metabolism;
Vitamin A/*blood;
Vitamin E/*blood;
Young Adult
- From:Korean Journal of Ophthalmology
2013;27(3):158-161
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate whether alterations in plasma vitamin A and E levels in patients with psoriasis have an effect on tear film changes. METHODS: Sixty-two eyes of 31 patients with psoriasis vulgaris (Group A) and 74 eyes of 37 age- and gender-matched control subjects (Group B) were included in the study. Ocular and medical histories and dietary habits were obtained from each patient. The tear film break-up time (TBUT), the Schirmer 1 test results and plasma vitamin A and E levels were evaluated. RESULTS: The mean Schirmer 1 test score was 14.76 +/- 6.12 mm/5 min in Group A and 15.69 +/- 3.10 mm/5 min in Group B. The mean plasma levels of vitamins A and E in Groups A and B were 1.86 +/- 0.62 micromol/L and 1.88 +/- 0.65 micromol/L vs. 26.21 +/- 5.13 micromol/L and 27.19 +/- 8.89 micromol/L, respectively. The Schirmer 1 test results and plasma vitamin A and E levels were not found to be significantly different between the groups (p > 0.05). The mean TBUT was 9.94 +/- 6.18 seconds in Group A and 14.47 +/- 5.65 seconds in Group B, a significant difference (p < 0.05). No correlation existed between plasma vitamin A and E levels, TBUT or the severity and duration of the disease (p > 0.05). CONCLUSIONS: Plasma vitamin A and E levels do not seem to be related to tear film changes in patients with psoriasis vulgaris.
