The Effect of Topical Cyclosporine 0.05% on Dry Eye after Cataract Surgery.
10.3341/kjo.2013.27.3.167
- Author:
Yeon Woong CHUNG
1
;
Tae Hoon OH
;
Sung Kun CHUNG
Author Information
1. Department of Ophthalmology, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. eyedoc@catholic.ac.kr
- Publication Type:Original Article ; Clinical Trial ; Research Support, Non-U.S. Gov't ; Randomized Controlled Trial
- Keywords:
Cataract surgery;
Cyclosporine;
Dry eye syndromes
- MeSH:
Aged;
Aged, 80 and over;
*Cataract Extraction;
Cyclosporine/*administration & dosage;
Dry Eye Syndromes/*drug therapy;
Female;
Humans;
Immunosuppressive Agents/administration & dosage;
Male;
Middle Aged;
Ophthalmic Solutions/*administration & dosage;
Postoperative Complications/*drug therapy;
Treatment Outcome
- From:Korean Journal of Ophthalmology
2013;27(3):167-171
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate the effectiveness of cyclosporine 0.05% for dry eye after cataract surgery. METHODS: Thirty-two newly diagnosed patients with dry eye syndrome 1 week after cataract surgery received a twice-daily treatment of cyclosporine 0.05% for one eye and normal saline 0.9% for the other. Disease severity was measured at 2 weeks, 1 month, 2 months, and 3 months by Schirmer test I (ST-I), tear film break-up time (tBUT), corneal temperature and dry eye symptom questionnaire (Ocular Surface Disease Index). RESULTS: Both groups increased in ST-I and tBUT over time. ST-I in the cyclosporine 0.05% group showed a significant increase at 3 months and tBUT in the cyclosporine 0.05% group showed an increase at 2 and 3 months. The dry eye symptom score was significantly reduced in the cyclosporine 0.05% group. CONCLUSIONS: Cyclosporine 0.05% can also be an effective treatment for dry eye after cataract surgery.
