Clinical and Neuroimaging Features of Moyamoya Disease.
- Author:
Oh Young KWON
1
;
Ki Jong PARK
;
Sung Chul JEON
;
Byeong Hoon LIM
Author Information
1. Department of Neurology, Gyeongsang National University College of Medicine.
- Publication Type:Original Article
- Keywords:
Moyamoya disease;
Ethmoid;
Vault
- MeSH:
Adult;
Age Distribution;
Age of Onset;
Aneurysm, False;
Angiography;
Arteries;
Cerebrovascular Disorders;
Child;
Circle of Willis;
Classification;
Constriction, Pathologic;
Diagnosis;
Female;
Hemorrhage;
Humans;
Infarction;
Male;
Medical Records;
Moyamoya Disease*;
Neuroimaging*;
Seizures;
Skull
- From:Journal of the Korean Neurological Association
1998;16(4):432-438
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Moyamoya disease is a chronic cerebrovascular disorders in which stenosis of the major arteries of the circle of Willis at the base of the skull progresses to occlusion. We observed two kinds of collateral pathways from the extracranial to the intracranial arteries. Also we evaluated clinlcal and neuroimaging features of moyamoya disease to give on aid in diagnosis. METHODS: We analysed 17 patients with moyamoya disease through the medical record and neuroimaging (conventional angiography and/or MR angiography) review. Six out of 17 patients were children(< OR =15 years) and the other 11 patients were adults(15 years). There were 8 males and 9 females. RESULTS: In our result, moyamoya disease was more common in the adult. There was bimodal age distribution, so average age of onset in children was 8-year-old and in adult 37-year-old. Common clinical features are seizure (66%), TIA (17%), and psychotic behavior (17%) in childrens and hemorrhages (73%), infarction (18%), seizures (9%) in adults. According to angiographic staging classification of Suzuki et al. (1967), our cases showed distribution of stage I (13%), stage II (8.8%), stage III (65.3%), stage IV (4.3%), stage V (4.3%), stage VI (4.3%). In collateral vessels of moyamoya disease, there were 7 cases of ethmoidal moyamoya, 3 of vault moyamoya and 1 of mixed form. It is interesting that there were five cases of unilateral moyamoya disease and one case had pseudoaneurysm. CONCLUSION: According to our results, we may say that seizures are common in the children and hemorrhages are in the adult. Unilateral moyamoya were mainly occurred in the adult. Ethmoidal collaterals were common among collaterals and stage III had a more cases than others in our neuroimaging data. These clinical and neuroimaging data may help interpretation and diagnosis of moyamoya disease.
