A Case of Rhabdomyolysis with Acute Renal Failure Due to Acute CO Poisoning.
- Author:
Soo Young JEONG
1
;
Jung Dal LEE
;
Jung Man KIM
;
Young Hyae KO
;
Myung Ho KIM
;
In Hyuk YOON
Author Information
1. Department of Pathology, Hanyang University.
- Publication Type:Case Report
- MeSH:
Acute Kidney Injury*;
Creatinine;
Extremities;
Hospitalization;
Hyperkalemia;
Kidney;
Mitochondria;
Myofibrils;
Oliguria;
Poisoning*;
Renal Insufficiency;
Rhabdomyolysis*
- From:Journal of the Korean Neurological Association
1985;3(1):83-89
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors studied one case with rhabdomyolysis associated with acute renal failure, which followed acute CO intoxication. Oliguria, hyperkalemia developed within one day of rhabdomyolysis on left extremities. During the first three days of hospitalization, rapid increase in serum BUN, serum creatinine and serum muscle enzymes (CPK, LDH, GPT, GOT) were noted. Renal failure was controlled by artifiral kidney. Several areas of increased uptake of technetium-99m DP were noticed on bone scan. Electron microscopic examinations of biopsied muscle consist of disarrangement of myofibrils, loss or destruction of Z-line, difficulties in distinguishing A-band from I-band, and swelling of mitochondrias. These findings suggest that acute CO poising may be followed by severe muscle destruction and renal damage.
