The Effect of Imaging Parameters of Diffusion Tensor Imaging on Fractional Anisotropy.
10.3348/jkrs.2007.57.4.315
- Author:
Jae Su JUN
1
;
Hyun Jeong KIM
;
Po Song YANG
;
Choong Gon CHOI
;
Sang Joon KIM
;
Jeong Hyun LEE
;
Sang Bong LEE
;
Seon Young RYU
;
Ji Chang KIM
Author Information
1. Deparment of Radiology, Dae Jeon, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea. rad_1970@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Brain;
Diffusion;
Magnetic resonance (MR);
Anisotropy
- MeSH:
Anisotropy*;
Brain;
Corpus Callosum;
Diffusion Tensor Imaging*;
Diffusion*;
Healthy Volunteers;
Putamen;
Signal-To-Noise Ratio
- From:Journal of the Korean Radiological Society
2007;57(4):315-322
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the effect of changes of parameters of diffusion tensor imaging (DTI), including slice thickness/slice number, b-value and the direction number of a diffusion gradient on fractional anisotropy (FA). MATERIALS AND METHODS: Three groups of normal volunteers underwent brain diffusion tensor imaging with the use of three different imaging parameters as follows: a different slice thickness/slice number (6 mm/20 slices and 2.33 mm/54 slices), a different b-value (800 s/mm2/1000 s/mm2) and a different number of directions of the diffusion gradient (6 and 15 directions). The signal to noise ratio (SNR) and FA were measured by a ROI measurement at the anterior corona radiata, superior corona radiata, putamen and corpus callosum. We compared the mean SNR and FA in each group by the use of the paired T-test. RESULTS: The SNR decreased and the FA increased significantly according to the increase of the slice number (6 mm/20 slices vs. 2.33 mm/54 slices). The SNR of DTI with 15 diffusion gradient directions was significantly higher than DTI with six directions, without a difference of FA. There were no significant changes of the SNR and FA of DTI according to the b-value. CONCLUSION: It is essential and useful in the clinical application of DTI to understand the effect of imaging parameters on FA.
