Prevention and Dissociation of the Platelet Aggregation in a Patient with EDTA-dependent Pseudothrombocytopenia by Supplementation of Kanamycin: A Case Report.
- Author:
In sang JEON
1
;
Sung Wan YANG
Author Information
1. Department of Pediatrics, Gachon Medical School, Incheon, Korea. isjeon@ghil.com
- Publication Type:Case Report
- Keywords:
Pseudothrombocytopenia;
EDTA;
Kanamycin
- MeSH:
Anticoagulants;
Blood Platelets*;
Child;
Citric Acid;
Edetic Acid;
Heparin;
Humans;
Kanamycin*;
Male;
Platelet Aggregation*;
Sodium
- From:Korean Journal of Pediatrics
2005;48(6):675-677
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pseudothrombocytopenia is usually associated with anticoagulant ethylene diaminetetraacetic acid (EDTA). The platelet clumping that occurs in EDTA-dependent pseudothrombocytopenia (EDPT) can sometimes be prevented by the use of other anticoagulants such as heparin or sodium citrate. As an alternative, we used kanamycin before or after the withdrawal of EDTA-anticoagulated blood in a 6-year-old boy with EDPT. Kanamycin used supplementarily during the differentiation of EDPT effectively prevented platelet clumping.
