Myxofibrosarcoma Originating from Chest Wall.
- Author:
Soon Ho CHOI
1
;
Byung Ki CHA
;
Mi Kyung LEE
;
Sam Youn LEE
;
Chong Bum CHOI
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Wonkwang University College of Medicine, Korea. shchoi@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Thorax neoplasm;
Fibrosarcoma;
Thorax
- MeSH:
Adult;
Aged;
Blood Vessels;
Drug Therapy;
Extremities;
Female;
Fibrosarcoma;
Humans;
Middle Aged;
Radiotherapy;
Sarcoma;
Skin;
Thoracic Wall*;
Thorax*;
Transplants;
Vimentin
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2006;39(2):166-170
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Myxofibrosarcoma represents one of the most common soft tissue sarcomas of the extremities in adult and elderly patients. However, it only rarely occurs in the chest wall. A 58 years old woman presented with a huge painless lump (8x6.5 cm) in the right lower parasternal area which recurred a few months following excision from General surgery of our hospital. Histology showed an infiltrative deep seated dermal and subcutaneous tumor. It had a distinctive lobular growth pattern with prominent myxoid change and moderate cellularity. Tumor cells were spindle-shaped with varying degrees of pleomorphism and frequent mitotic figures. Numerous blood vessels with curvilinear growth pattern were also seen. Immunostains for S-100, CD68, Mac 387, and FX IIIa were all negative, but positive for Vimentin. The histologic feature was of an intermediate grade myxofibrosarcoma. Wide excision was performed and recovered in good condition without any physical disabilities and was discharged at one month later. Currently she is waiting for the skin graft without chemotherapy and radiotherapy.
