Rhabdomyolysis Associated With Statin Medication, Exercise and Sauna.
10.4070/kcj.2008.38.5.284
- Author:
Young Ho HONG
1
;
Hyeon Seon WON
;
Do I KIM
;
Su Hee LEE
;
Tae Sun KIM
;
Yun Yong SEO
;
Jeong Bae PARK
;
Il Soon WHANG
;
Hyun Ho SHIN
Author Information
1. Department of Internal Medicine, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. dudghaudwn@hanmail.net
- Publication Type:Case Report
- Keywords:
Rhabdomyolysis;
Statin;
Exercise;
Sauna
- MeSH:
Creatine Kinase;
Dyslipidemias;
Electrolytes;
Female;
Humans;
Hydroxymethylglutaryl-CoA Reductase Inhibitors;
Lower Extremity;
Middle Aged;
Muscle Weakness;
Muscle, Skeletal;
Myoglobin;
Proteins;
Rhabdomyolysis;
Simvastatin;
Steam Bath
- From:Korean Circulation Journal
2008;38(5):284-286
- CountryRepublic of Korea
- Language:English
-
Abstract:
Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle, and this causes myoglobin and other intracellular proteins and electrolytes to leak into the circulatory system. We report here on a case of rhabdomyolysis associated with statin, exercise and sauna exposure. A 63-year-old woman presented to our hospital, and she had been taking simvastatin for over 6 years due to dyslipidemia. She complained of developing myalgia and weakness of the lower extremities over the previous 5 days. She had used a sauna more than 4 hours daily for 20 years, and she had started unaccustomed exercise in the sauna 1 week prior to admission. Her serum creatine kinase concentration was 45,990 IU/L. Conservative treatment was started with the discontinuation of her statin medication, exercise and use of the sauna. Her symptoms and serum creatine kinase level decreased 1 week after admission and she was discharged with minimal residual muscle weakness.