A Case of Histiocytic Medullary Reticulosis with Cutaneous Lesions.
- Author:
Kyung Joon JEON
;
Dong Woog YOO
;
Yong Whan KIM
;
Dong Wha LEE
- Publication Type:Original Article
- MeSH:
Acute Disease;
Anemia;
Biopsy;
Dermis;
Fever;
Histiocytes;
Humans;
Jaundice;
Leukopenia;
Lymphatic Diseases;
Male;
Middle Aged;
Mononuclear Phagocyte System;
Purpura;
Skin;
Thrombocytopenia;
Weight Loss
- From:Korean Journal of Dermatology
1980;18(6):579-584
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Histiocytic medullary reticulosis is a rare, uniformly fatal, acute disease of the reticuloendothelial system. The disease is associated with fever, malaise, weakness, weight loss, lymphadenopathy, hepatosplenomegaly, jaundice, and purpura. Common laboratory findings are severe anemia, leukopenia, and thrombocytopenia. A 49-year-old male patient is described who had multiple purple nodules and tumors in the skin. A biopsy taken from a skin lesion showed a diffuse proliferation of atypical histiocytes in the dermis and subcutaneous tissue.However, erythrophagocytosis of these atypical histiocytes was not seen.
