Tuberous Sclerosis Occuring through 3 Generations.
- Author:
Jong Seop HA
;
Byung Jin LEE
;
Sang Lip CHUNG
- Publication Type:Original Article
- MeSH:
Angiofibroma;
Family Characteristics*;
Humans;
Intellectual Disability;
Seizures;
Siblings;
Tuberous Sclerosis*
- From:Korean Journal of Dermatology
1980;18(6):605-611
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tuberous sclerosis is a complex neurocutaneous disease inherited as an autosomal dominant pattern, which is characterized by facial angio-fibroma, mental retardation and seizures. Many cases have been reported in the literatures, but familial cases are relatively rare. We present 9 cases of tuberous sclerois occuring througb 3 generations, which are 3 cases of angiofibroma, mental retardation and seizures, 2 cases of facial angiofibroma and seizures, 1 case of mental retardation and seizures and 3 cases who showed facial angiofibroma only. Two brothers in this family reveald icthyosis vulgaris without tuberous sclerosis.
