Brain Regulation of Energy Metabolism.
10.3803/EnM.2016.31.4.519
- Author:
Eun ROH
1
;
Min Seon KIM
Author Information
1. Department of Biomedical Science, University of Ulsan College of Medicine, Seoul, Korea.
- Publication Type:Review
- Keywords:
Hypothalamus;
Brain stem;
Energy metabolism;
Obesity
- MeSH:
Autonomic Nervous System;
Brain Stem;
Brain*;
Energy Intake;
Energy Metabolism*;
Homeostasis;
Hyperphagia;
Hypothalamus;
Ideal Body Weight;
Metabolism;
Neurons;
Obesity;
Pathology
- From:Endocrinology and Metabolism
2016;31(4):519-524
- CountryRepublic of Korea
- Language:English
-
Abstract:
In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity. The brain detects body energy excess and deficit by sensing the levels of circulating metabolic hormones and nutrients and by receiving metabolic information from the periphery via the autonomic nervous system. A specialized neuronal network coordinates energy intake behavior and the metabolic processes affecting energy expenditure. Here, we briefly review neuronal mechanisms by which our body maintains energy balance.
