Anaphylactoid reaction to ofloxacin with cross-reactivity to other fluoroquinolones.
- Author:
Cheol Woo KIM
1
;
Duk Young KIM
;
Sung Tae RYU
;
Sang Yong KANG
;
Chang Soo JANG
Author Information
1. Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. cwkim1805@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Anaphylatoid reaction;
ofloxacin;
fluoroquinolones;
cross-reactivity
- MeSH:
Anti-Infective Agents;
Ciprofloxacin;
Fluoroquinolones*;
Humans;
Hypersensitivity;
Ofloxacin*
- From:Journal of Asthma, Allergy and Clinical Immunology
2004;24(1):146-151
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fluoroquinolones are antimicrobial agents that have a broad range of activity against both gram-negative and gram-positive organisms. Anaphylactoid reactions have been sporadically reported with fluoroquinolones. There have been a few reports that describes cross-reactivity between fluoroquinolones. We experienced a case of ofloxacin-induced anaphylactoid reaction, and confirmed cross-reactivity between ofloxacin and ciprofloxacin with the oral challenge test. Cross-reactivity between fluoroquinolones may be important, and avoidance of any fluoroquinolones should be mandatory for patients with hypersensitivity reaction to one of these drugs.
