Correlates of Cognitive Impairment of Rheumatic Disease: Systematic Review and Meta-analysis.
- Author:
Jina MO
1
;
Jisuk PARK
;
Hyunsoo OH
Author Information
- Publication Type:Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
- Keywords: Cognition disorders; Rheumatic diseases; Review; Meta-analysis
- MeSH: Anxiety; Cognition; Cognition Disorders/complications/*pathology; Databases, Factual; Depression/complications; Humans; Hypertension/complications; Obesity/complications; Rheumatic Diseases/complications/*pathology; Risk Factors
- From:Journal of Korean Academy of Nursing 2016;46(1):1-18
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensional correlates of rheumatic disease through a systematic literature review and meta-analysis. METHODS: For the study purpose, 23 studies were selected through a systematic process of searching the literature. RESULTS: The study results showed that among general characteristics, age and education were the variables having a significant relationship with cognitive impairment. Among health risk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertension were shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of the physiological factor, had significant association with cognitive impairment. None of the medication related factors had a significant relationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationship with cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship with cognitive impairment. CONCLUSION: The findings indicate that the variables strongly impacting on cognitive impairment in rheumatic disease are depression and disease activity.
