A Case of Non Secretory Type Multiple Myeloma Associated with Systemic Lupus Erythematosus.
10.4078/jkra.2010.17.4.431
- Author:
Yu Jin JEONG
1
;
Hyun Sook KIM
;
Eun Jeong KIM
;
Yun Sung KIM
;
Chi Young PARK
;
Bong Seok SHIN
;
Geon PARK
Author Information
1. Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea. healthyra@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Nonsecretory multiple myeloma;
Systemic lupus erythematosus
- MeSH:
Anemia, Refractory;
Autoantibodies;
Autoimmune Diseases;
Humans;
Hypergammaglobulinemia;
Immunoglobulin G;
Immunoglobulins;
Incidence;
Lupus Erythematosus, Systemic;
Multiple Myeloma
- From:The Journal of the Korean Rheumatism Association
2010;17(4):431-436
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The development of malignant tumors is a more frequent finding in lupus patients than the general population. However, the incidence of multiple myeloma associated with systemic lupus erythematosus (SLE) is a rare manifestation. SLE is an autoimmune disease characterized by B cell hyperactivity, formation of autoantibodies, and multi-clonal hypergammaglobulinemia. Serum immunoglobulin increases, with a specific increase in IgG, which is due to an increase in autoantibody formation related to extrinsic and intrinsic antigens. We report on a patient with SLE combined with IgG, lambda type nonsecretory multiple myeloma, which was diagnosed with refractory anemia and hypergammaglobulinemia.
