Usefulness of the Doppler Flow of the Ophthalmic Artery in the Evaluation of Carotid and Coronary Atherosclerosis.
10.4070/kcj.2014.44.6.406
- Author:
Seung Pyo HONG
1
;
Yon Woong PARK
;
Chan Wook LEE
;
Joung Won PARK
;
Kyung Ryun BAE
;
Seung Woon JUN
;
Young Soo LEE
;
Jin Bae LEE
;
Jae Kean RYU
;
Ji Yong CHOI
;
Sung Guk CHANG
;
Kee Sik KIM
Author Information
1. Department of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea. kks7379@cu.ac.kr
- Publication Type:Original Article
- Keywords:
Atherosclerosis;
Carotid arteries;
Coronary vessels;
Ophthalmic artery;
Ultrasound
- MeSH:
Atherosclerosis;
Carotid Arteries;
Carotid Intima-Media Thickness;
Coronary Angiography;
Coronary Artery Disease*;
Coronary Stenosis;
Coronary Vessels;
Humans;
Male;
Ophthalmic Artery*;
Retrospective Studies;
Ultrasonography
- From:Korean Circulation Journal
2014;44(6):406-414
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: There is little information about the relationship between the Doppler flow of the ophthalmic artery (OA) and carotid and coronary atherosclerosis. The aim of the investigation was to assess the clinical usefulness of the Doppler flow of the OA to estimate the severity of carotid and coronary atherosclerosis. SUBJECTS AND METHODS: The study was a retrospective analysis of the findings in 140 patients (mean age: 60 years, male: 64%) who underwent coronary angiography (CA) for the evaluation of typical angina between July 2010 and October 2011 in our single center. The severity of coronary artery stenosis was based on the Gensini score (GS). Significant coronary artery disease (CAD) was defined as the obstruction of over 75% of the major coronary arteries confirmed with CA. The pulsed Doppler flow of the OA and carotid ultrasound were performed before CA. RESULTS: The mean systolic velocity/mean diastolic velocity (MSV/MDV), pulsatile index and resistance index in the Doppler flow of the OA were identified as significant and independent correlations with carotid intima-media thickness, and MSV/MDV was identified to have a significant and independent correlation with the GS. MSV/MDV >2.1 was the independent predictor for significant CAD {odds ratio (OR) 3.8, 95% confidence interval (CI) 1.5-9.7, p=0.005} and carotid plaque (OR 2.8, 95% CI 1.1-7.0, p=0.028), after adjustment for CAD-associated factors. CONCLUSION: The Doppler flow of the OA might be a useful predictor of the severity of carotid and coronary atherosclerosis.