Rapid Progression of Diabetic Glomerulosclerosis with Crescents to End-stage Renal Disease in Newly Diagnosed Type 2 Diabetes.
- Author:
Young Sun KO
1
;
Hyaejin YUN
;
Eun Young LEE
;
Kiseok JANG
;
Joo Hark YI
;
Sang Woong HAN
Author Information
- Publication Type:Case Report
- Keywords: Diabetic nephropathies; Disease progression; Pathology
- MeSH: Adult; Biopsy; Diabetes Mellitus, Type 2; Diabetic Nephropathies*; Diabetic Retinopathy; Diagnosis; Disease Progression; Glomerular Filtration Rate; Glomerulonephritis; Humans; Kidney; Kidney Failure, Chronic*; Male; Nephrotic Syndrome; Pathology
- From:Korean Journal of Medicine 2016;90(1):46-49
- CountryRepublic of Korea
- Language:English
- Abstract: Diabetic nephropathy is a chronic microvascular complication of type 2 diabetes and the leading cause of end-stage renal disease. We report the case of a 34-year-old male, newly diagnosed with type 2 diabetes mellitus, who had advanced-stage nephropathy with glomerular crescents. A moderately-to-severely decreased glomerular filtration rate with nephrotic syndrome was seen at the time of diagnosis of diabetes. Proliferative diabetic retinopathy was detected, but there was no positive finding in serology tests for glomerulonephritis. Non-necrotizing cellular crescents and nodular glomerulosclerosis were observed in a kidney biopsy, and renal function declined rapidly to the end stage. We review data on diabetic glomerulosclerosis with cellular crescents and the rapid progression of nephropathy.
