Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding.
10.3904/kjim.2016.31.1.54
- Author:
Yoo Jin LEE
1
;
Bo Ram MIN
;
Eun Soo KIM
;
Kyung Sik PARK
;
Kwang Bum CHO
;
Byoung Kuk JANG
;
Woo Jin CHUNG
;
Jae Seok HWANG
;
Seong Woo JEON
Author Information
1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. dandy813@hanmail.net
- Publication Type:Observational Study ; Original Article
- Keywords:
Gastrointestinal hemorrhage;
Mortality;
Prognosis;
Comorbidity
- MeSH:
Adult;
Age Factors;
Aged;
Chi-Square Distribution;
Comorbidity;
Diabetes Mellitus/mortality;
Endoscopy, Gastrointestinal;
Female;
Gastrointestinal Hemorrhage/diagnosis/*mortality/physiopathology/therapy;
Hemodynamics;
Hospital Mortality;
Hospitalization;
Humans;
Logistic Models;
Male;
Middle Aged;
Multivariate Analysis;
Neoplasm Metastasis;
Odds Ratio;
Predictive Value of Tests;
Prospective Studies;
Republic of Korea;
Risk Assessment;
Risk Factors;
Time Factors;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2016;31(1):54-64
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition. METHODS: A prospective observational study was conducted at a single hospital between April 2010 and November 2012, and 336 patients with symptoms and signs of gastrointestinal bleeding were consecutively enrolled. Clinical characteristics and endoscopic findings were reviewed to identify potential factors associated with 30-day mortality. RESULTS: Overall, 184 patients were included in the study (men, 79.3%; mean age, 59.81 years), and 16 patients died within 30 days (8.7%). Multivariate analyses revealed that comorbidity of diabetes mellitus (DM) or metastatic malignancy, age > or = 65 years, and hypotension (systolic pressure < 90 mmHg) during hospitalization were significant predictive factors of 30-day mortality. CONCLUSIONS: Comorbidity of DM or metastatic malignancy, age > or = 65 years, and hemodynamic instability during hospitalization were predictors of 30-day mortality in patients with NVUGIB. These results will help guide the management of patients with this condition.
