A Case of Treatment with Steroid and Hydrochloroquine of Thrombocytopenia in Primary Sjögren's Syndrome.
10.7180/kmj.2017.32.1.118
- Author:
Yeong Seop YUN
1
;
Ji Wook CHOI
;
Young Jae DOO
;
Tae Hyung KIM
;
Hye Lim OH
;
Ji Min OH
Author Information
1. Department of Internal Medicine, Anyang SAM Hospital, Anyang, Gyeonggi-do, Korea. ninijang@hanmail.net
- Publication Type:Case Report
- Keywords:
Hydroxychloroquine;
Primary Sjögren's syndrome;
Steroid;
Thrombocytopenia
- MeSH:
Anemia;
Autoimmune Diseases;
Female;
Humans;
Hydroxychloroquine;
Leukopenia;
Lymphoproliferative Disorders;
Middle Aged;
Platelet Count;
Thrombocytopenia*
- From:Kosin Medical Journal
2017;32(1):118-126
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sjögren's syndrome is a systemic autoimmune disease characterized by sicca symptoms and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders are well-known extraglandular, hematological complications of Sjögren's syndrome. These hematologic alterations are usually mild and respond well with steroid therapy. We report a case of a 52-year-old female patient who was initially presented with thrombocytopenia. The patient was then diagnosed with primary Sjögren's syndrome and initially treated with steroid. The patient's platelet count was decreased when steroid was tapered. The dose of steroid could be effectively reduced after combined medication with hydroxychloroquine.
