Two Cases of Sertoli-Leydig Cell Tumor without Masculinized Symptom.
- Author:
Chang Yeal SHIN
1
;
Byeoung Uk HA
;
Heung Ro KIM
;
Pyoung Kuk KIM
;
Jeoung Wook KIM
;
Kang Kook LEE
Author Information
1. Department of Obstetrics and Gynecology, Wallace Memorial Baptist Hospital, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Sertoli-Leydig cell tumors;
alpha-fetoprotein;
Testosterone
- MeSH:
Adult;
alpha-Fetoproteins;
Amenorrhea;
Biopsy;
Female;
Gonads;
Humans;
Middle Aged;
Ovarian Neoplasms;
Sertoli-Leydig Cell Tumor*;
Testosterone;
Virilism
- From:Korean Journal of Obstetrics and Gynecology
1997;40(9):2087-2091
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sertoli-Leydig cell tumor is an uncommon tumor that may manifest itself by a characteri-stic virilization symptom. It is a rare gonadal tumor of sex-cord type, representing only 0.1~0.5% of all primary ovarian neoplasm. These tumors are the most common virilizing tumors in women of reproductive age. However, only one-third of patients develop masculinization. We have seen two cases of Sertoli-Leydig cell tumors without the virilizing symptom. These two cases have been confirmed by permanent tissue biopsies and have been presented in a 32-year old female who has had only amenorrhea and in a 56-year old postmenopausal female who has not manifested virilizing symptom. These cases are presented with brief review of the literature.
