Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae: The First Reported Case in South Korea.
10.4046/trd.2015.78.4.432
- Author:
Suk Hyeon JEONG
1
;
Su Young KIM
;
Hyun LEE
;
Jun Soo HAM
;
Keum Bit HWANG
;
Subin HWANG
;
Sun Hye SHIN
;
Myung Jin CHUNG
;
Seung Heon LEE
;
Sung Jae SHIN
;
Won Jung KOH
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wjkoh@skku.edu
- Publication Type:Case Report
- Keywords:
Bronchiectasis;
Mycobacterium;
Nontuberculous Mycobacteria
- MeSH:
Azithromycin;
Bronchiectasis;
Ethambutol;
Female;
Follow-Up Studies;
Humans;
Korea*;
Lung Diseases*;
Lung*;
Middle Aged;
Mycobacterium*;
Nontuberculous Mycobacteria;
Radiography;
Rifampin;
Sputum;
Thorax
- From:Tuberculosis and Respiratory Diseases
2015;78(4):432-435
- CountryRepublic of Korea
- Language:English
-
Abstract:
This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.
