Usefulness of Tc-99m MIBI Scan in the Postoperative Follow Up Of Well-Differentiated Thyroid Cancer.
- Author:
Chong Soon KIM
;
Hyun Kyung LEE
;
Jae Soon SONG
;
Joon Jae SHINN
;
Kye Hwa YOU
;
Wang Ki CHA
;
Eun Sil KIM
;
Do Min KIM
- Publication Type:Original Article
- Keywords:
Tc-99m MIBI scan;
I-131 scan;
Thyroid cancer;
Thyroglobulin
- MeSH:
Follow-Up Studies*;
Humans;
Thyroglobulin;
Thyroid Gland*;
Thyroid Neoplasms*
- From:Korean Journal of Nuclear Medicine
1997;31(3):356-364
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the clinical utility of Tc-99m MIBI scan in the detection of residual thyroid tissue or metastatic lesion in postoperative thyroid cancer patients, we compared Tc-99m MIBI scan with I-131 diagnostic and therapeutic scan in 30 postoperative well-differentiated thyroid cancer patients. Thyroglobulin levels of both on and off thyroid hormone medication and antithyroglobulin antibody were tested [Tg(on), Tg(off)l Positive rates for I-131 diagnostic and Tc-99m MIBI scan were 81% and 68% respectively. Concordance between I-131 diagnostic and Tc-99m MIBI scan was observed in 15 cases; 12 positive and 3 negative respectively Among the 6 cases with negative I-131 diagnostic scan and positive Tc-99m MIBI scan, 4 were positive in the therapeutic I-131 scan. We concluded that Tc-99m MIBI scan maybe a useful complementary modality to the currently established method of I131 scan and serum thyroglobulin level in the detection of recurrent or metastatic thyroid cancer, especially in the case of negative I-131 diagnostic scan.
