The Additive Effect of Trusopt to Beta-blockers in the Treatment of Glaucoma Patients.
- Author:
Kyoung Seob LEE
1
;
Gong Je SEONG
Author Information
1. The Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Glaucoma;
IOP;
Beta blockers;
Trusopt
- MeSH:
Burns;
Glaucoma*;
Humans;
Ophthalmic Solutions
- From:Journal of the Korean Ophthalmological Society
1998;39(2):369-374
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intraocular pressure(IOP) and side effects of adding Trusopt to beta blockers was studied in 39 eyes of 22 glaucoma patients that was inadequately controlled with beta blockers alone. Routine eye examination and IOP measurement were performed before the additive therapy. Trusopt eye drops were topically applied three times a day with previously used three kinds of beta blockers. IOP was measured at 1 week, 1 month, and 3 month after the combined therapy. Mean IOP was 18.1+/-5.2mmHg before combined therapy; 15.3+/-4.0mmHg after 1week, 15.2+/-3.2mmHg after 1 month and 15.0+/-3.4mmHg after 3 month of therapy. Side effects of combined therapy were bitter taste(20.5%), burning sensation(9.6%) redness(5.1%), discomfort(5.1%), and ocular pain(5.1%). These results indicate that adding Trusopt in patients treated with beta blockers cause a further reduction of IOP that may prove to be clinically useful in glaucoma therapy.
