The Change of Thyroid Stimulating Hormone Values of Healthy Subjects According to Temperature and Aging.
10.7180/kmj.2014.29.2.125
- Author:
Sung Su KIM
1
;
Dong Hoon LEW
;
Ja Yoon CHOI
;
Eun Ju LEE
;
Min Gyo KIM
;
Kyong Young KIM
;
Soo Kyoung KIM
;
Jung Hwa JUNG
;
Jae Hoon JUNG
;
Jong Ryeal HAHM
Author Information
1. Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.
- Publication Type:Original Article
- Keywords:
Reference range for TSH;
TSH;
Variation of TSH
- MeSH:
Aging*;
Female;
Gyeongsangnam-do;
Humans;
Male;
Reference Values;
Thyroid Gland;
Thyrotropin*;
Ultrasonography
- From:Kosin Medical Journal
2014;29(2):125-134
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: We conducted a study to investigate the normal range for TSH and within-individual variations of TSH according to temperature and aging. PATIENTS AND METHODS: We enrolled patients who underwent periodic medical examinations five times over a six year period (2007.8~2013.6). Anthropometric data and thyroid ultrasonography were evaluated, and serum TSH, T3, and T4 were assayed. RESULTS: Subjects were 19-64 years old, 120 were female, and 208 were male. Reference ranges for TSH were 0.53-4.94 mIU/L in the first test, 0.49-5.61 mIU/L in the second test, 0.46-6.06 mIU/L in the third test, 0.48-5.99 mIU/L in the fourth test, and 0.52-6.3 mIU/L in the fifth test. When the TSH level was analyzed according to temperature and sex, mean TSH was higher in months in which the average monthly temperatures were below 10degrees C in Jinju, Gyeongnam and female. The aging and low temperatures are associated with increased serum TSH concentrations in the within-individual. CONCLUSIONS: This study showed that aging is associated with increased serum TSH concentrations in the within-individual and serum TSH concentrations are different in the within-individual according to the temperature.
