A Case of Cutaneous Side Reaction of Collagen Implantation.
- Author:
Sung Wook KIM
;
Jun Young LEE
;
Chung Won KIM
- Publication Type:Case Report
- Keywords:
Collagen Implantation;
Cutaneous Side Reaction
- MeSH:
Adult;
Collagen*;
Dermis;
Female;
Humans
- From:Korean Journal of Dermatology
1994;32(1):134-138
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Injectable Collagen Implan, is composed of purified bovine dermal collagen emulsified in saline and lidocaine(0.3%) base, and has been promoted for correction of soft tissue contour defects. Although collagen is a relatively nontoxic, nonimmunologic and biolegically nonreactive biomaterial, some side reactions have been reported. We report herein a case of cutaneous side reaction to collagen implantation in a 38-year-old female. The patient presented with puritic, irritating, multiple, erythematous nodules on both the temporal and interorbital area, which had been observed since 1 day after collagen(KOKEN ATELOCOLLA-GEN IMPLANT-Japan) implantation. Histopathologic findings showed dense infiltration of acute and chronic inflammatory cells in the dermis, especially the perivascular and periadnexal area.
