Primitive Neuroectodermal Tumor of the Kidney.
- Author:
Gi Young KIM
1
;
Sung Won LEE
;
Sung Chul PARK
;
Seung Hoon CHO
;
Sun Il KIM
;
Young Nam WOO
;
Tchun Yong LEE
;
Moon Hyang PARK
Author Information
1. Department of Urology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Primitive neuroectodermal tumor (PNET);
Immunotherapy;
Kidney
- MeSH:
Adult;
Chromatin;
Diagnosis;
Female;
Humans;
Immunotherapy;
Kidney*;
Negative Staining;
Nephrectomy;
Neuroectodermal Tumors, Primitive*;
Rosette Formation;
Sarcoma, Ewing;
Synaptophysin;
Thoracic Wall
- From:Korean Journal of Urology
2004;45(2):181-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primitive neuroectodermal tumor (PNET), also referred to as extraskeletal Ewing's sarcoma, is a highly aggressive tumor, and it is seen typically in the soft tissues of the chest wall and paraspinal region but rarely arises in the kidney. A 27-year-old woman was presented with a left renal mass and underwent a radical nephrectomy. The pathological diagnosis was a primitive neuroectodermal tumor. Microscopically, there were sheets and lobules of cells with round to oval nuclei and coarse chromatin, as well as a Homer Wright rosette formation. Immunohistochemical analysis showed strongly positive staining of CD99 and negative staining of other neuroendocrine markers, such as synaptophysin and chromogranin.
