Host Immune Responses Against Hog Cholera Virus in Pigs Treated with an Ionized Alkali Mineral Complex.
- Author:
Bong Kyun PARK
1
;
Kwang Soo LYOO
;
Yong Ho PARK
;
Jong Ho KOH
;
Kyung Suk SEO
Author Information
1. College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, 441-744 Suwon, Korea. parkx026@snu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Ionized alkali mineral complex;
Hog cholera virus;
Porcine immune cells
- MeSH:
Alkalies/immunology/*pharmacology;
Animals;
Antibodies, Viral/blood;
Classical Swine Fever/*immunology/prevention & control;
Classical swine fever virus/*immunology;
Flow Cytometry/veterinary;
Fluorescent Antibody Technique, Indirect/veterinary;
HLA Antigens/immunology;
Minerals/immunology/*pharmacology;
Swine;
Vaccination/*veterinary;
Vaccines, Attenuated/immunology;
Viral Vaccines/*immunology
- From:Journal of Veterinary Science
2002;3(4):315-319
- CountryRepublic of Korea
- Language:English
-
Abstract:
To determine the immune responses in pigs to hog cholera virus after treatment with an ionized alkali mineral complex (IAMC), 40 healthy pigs (28-32 days old) from a commercial swine farm were purchased and housed into 4 groups (n=10 each). All pigs were vaccinated intramuscularly (1 ml) with an attenuated live hog cholera virus (HCV, LOM strain) at 28-32 days old and challenged with a virulent hog cholera virus at 8 weeks after vaccination. Each group was treated with PowerFeelTM sprayed diet as 0.05% (w/w) in a final concentration (T-1, n=10), a diet mixed with SuperFeedTM as 3% (w/w) in a final concentration (T-2, n=10), or a diluted PowerFeelTM solution (1:500, v/v) as drinking water (T-3, n=10), respectively. A group (n=10) served as a non-treated control. Proportions of expressing CD2+ and CD8+ cells increased significantly (p<, 0.05) at 8-week post-application. Mean antibody titers of each group against HCV gradually increased to higher levels after vaccination and with challenge of the virulent virus. In conclusion, the IAMC-treated diets can be helpful for the improvement of growth in pigs with proper vaccination program, while the IAMC-treated diets have no effects on the clinical protection against hog cholera.
