Allergens Causing Atopic Diseases in Canine.
- Author:
Hwa Young YOUN
1
;
Hyung Seok KANG
;
Dong Ha BHANG
;
Min Kue KIM
;
Cheol Yong HWANG
;
Hong Ryul HAN
Author Information
1. Department of Internal Veterinary Medicine, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Korea. doglover@chollian.net
- Publication Type:Original Article
- Keywords:
canine atopic disease;
intradermal skin test (IDST);
allergens;
house dust mites
- MeSH:
Allergens/*immunology;
Animals;
Dermatitis, Atopic/immunology/*veterinary;
Dog Diseases/*immunology;
Dogs;
Female;
Male;
Skin Tests/veterinary
- From:Journal of Veterinary Science
2002;3(4):335-341
- CountryRepublic of Korea
- Language:English
-
Abstract:
Canine atopic skin disease is seasonal or sometimes non-seasonal immune-mediated skin disease which occurs commonly in Korea. The definite clinical sign is systemic pruritus, especially on periocular parts, external ear, interdigit spaces and lateral flank. For diagnosis of this dermatitis, complete history taking followed by intradermal skin test and serum in vitro IgE test needs to be performed. Allergen selection for the diagnosis and treatment of atopic dermatitis should be varied geographically. In this study, with intradermal skin test(IDST) the prevalence of atopic disease and what allergens are involved in are researched. Allergens used for IDST included 26 allergen extracts from six allergen groups: grasses, trees, weeds, molds, epidermal allergens and environmental allergens. The number of allergens was 42 in which the positive and negative controls are included. The most common positive allergen reaction was the house dust mites on IDST(22/35, 63%). The other positive allergen reactions were to flea(3/35, 9%), molds(1/35, 3%), house dusts(2/35, 6%), feathers (1/35, 3%), cedar/juniper(1/35, 3%), timothy grass(1/35, 3%) and dandelion(1/35, 3%). In this study, the most prevalent allergen causing atopic dermatitis in dogs in Korea was the house dust mites followed by the flea.