Surgery for Locally Advanced Non-Small Cell Lung Cancer.
- Author:
Young Tae KIM
1
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine, Cancer Research Institute, Korea. ytkim@plaza.snu.ac.kr
- Publication Type:Review
- Keywords:
NSCLC;
Surgery
- MeSH:
Carcinoma, Non-Small-Cell Lung*;
Drug Therapy;
Humans;
Lung Neoplasms;
Lymph Nodes;
Mortality
- From:Journal of Lung Cancer
2002;1(1):9-14
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Surgical resection of locally advanced lung cancer is a challenging subject for thoracic surgeons. Although the operative mortality and morbidity have recently decreased, extended pulmonary resection still remains a high-risk procedure. In selective patients an extended resection would offer an increased chance of a cure from the disease. The most important prognostic factors for a locally advanced lung cancer are the mediastinal lymph node status and the completeness of the resection. Careful preoperative evaluations are required, and every effort to achieve a negative resection margin is of utmost importance during the operation. The recent development of neoadjuvant chemotherapy seems to be promising, but to draw any conclusion regarding the long-term survival benefits, multi-centered randomized trials are mandatory.
