The Association between Helicobacter pylori Infection and Body Weight among Children.
10.5223/pghn.2016.19.2.110
- Author:
Jun Sik CHOI
1
;
Kyung Og KO
;
Jae Woo LIM
;
Eun Jeong CHEON
;
Gyung Min LEE
;
Jung Min YOON
Author Information
1. Department of Pediatrics, Konyang University College of Medicine, Daejeon, Korea. jmyoon@kyuh.ac.kr
- Publication Type:Original Article
- Keywords:
Helicobacter;
Obesity;
Body weight;
Disease eradication;
Child
- MeSH:
Amoxicillin;
Body Weight*;
Child*;
Clarithromycin;
Disease Eradication;
Female;
Helicobacter pylori*;
Helicobacter*;
Humans;
Immunoglobulin G;
Obesity;
Omeprazole;
Prevalence;
Retrospective Studies;
Weight Gain;
Weights and Measures
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2016;19(2):110-115
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We performed to reveal the association between the Helicobacter pylori infection and body weight among children. METHODS: Out retrospective study included patients who underwent the H. pylori immunoglobulin G testing at Konyang University Hospital between March 2011 and June 2014. These patients were classified as seropositive (28 boys, 27 girls; mean age: 9.89±3.28 years) or seronegative (55 boys, 54 girls; mean age: 9.84±3.02 years). Next, we compared various characteristics between the seropositive and negative groups, as well as between obese children (body weight ≥90th percentile) and non-obese children (body weight <90th percentile). Furthermore, we compared the change in body weight after 2 months of treatment with amoxicillin, clarithromycin and omeprazole among the 55 seropositive children (14 treated children and 41 non-treated children). RESULTS: There were no differences in the weights and laboratory data for the 55 seropositive children and 109 seronegative children (weight; 40.96±18.11 kg vs. 36.85±13.72 kg, respectively; p=0.14). And, there was no difference in the prevalence of H. pylori infection among the 29 obese and 135 non-obese children (p=0.581). However, after 2 months of eradication, the 14 treated patients exhibited a significant weight gain (+0.91±0.52 kg), compared to the 41 non-treated patients (-0.29±1.16 kg, p=0.025). CONCLUSION: Our findings present that obesity was not associated with the H. pylori infection, although H. pylori eradication led to significant increase in body weight.
