Introduction of Electrochemical Therapy (EChT) and Application of EChT to The Breast Tumor.
10.4048/jbc.2007.10.2.162
- Author:
Dae Sung YOON
1
;
Yu Mi RA
;
Dae gyung KO
;
Yun Me KIM
;
Keum Won KIM
;
Hoi Young LEE
;
Yu Ling XIN
;
Wei ZHANG
;
Zing Hong LI
;
Hee Uk KWON
Author Information
1. Department of General Surgery, Konyang University Hospital, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Electrochemical therapy;
Breast cancer;
Hemangioma
- MeSH:
Animals;
Breast Neoplasms*;
Breast*;
Drug Therapy;
Female;
Hemangioma;
Humans;
Mice;
Mice, Nude;
Necrosis;
Radiotherapy;
Recurrence
- From:Journal of Breast Cancer
2007;10(2):162-168
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To introduce the history and principle mechanism of electrochemical treatment (EChT) with animal study and report two cases successfully treated breast cancer and hemangioma by EChT. METHODS: In animal study, the breast cancer tumor in nude mouse treated with EChT (100 Coulomb/cm3) were reviewed for histologic changes. In the case studies, we reported method of EChT and clinical results after EChT. Case 1: 74 yr old female with locally advanced breast cancer received 3 times EChT with 1,000 Coulomb/time, 8 Volt. Case 2: 51 yr old female with breast hemagioma received one time EChT with 80 Coulomb, 8 Volt. RESULTS: In animal study, There were destructive change including vaculated cell fragment and extensive coagulative necrosis. Case 1 showed no local recurrence during 18 monthes after EChT. Case 2 also showed no evidence of recurrence of hemangioma. CONCLUSION: The EChT is easy to use. It is effective, safe, less traumatic and makes patients recover quickly. This is a new and effective method to treat patients with tumours that are inoperable and can not receive chemotherapy or radiotherapy.
