Change of Ionized Calcium following Blood Transfusion during Hepatic Lobectomy.
10.4097/kjae.1992.25.6.1093
- Author:
Gyu Wan KIM
1
;
Chee Mahn SHIN
;
Joo Yuel PARK
Author Information
1. Department of Anesthesiology, Pusan Paik Hospital, Inje University, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Transfusion;
Citrate;
Calcium
- MeSH:
Blood Transfusion*;
Brain;
Calcium*;
Citric Acid;
Depression;
Humans;
Hypocalcemia
- From:Korean Journal of Anesthesiology
1992;25(6):1093-1099
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Citrate in transfused blood forms a complex with calcium and decreases the free ionized calcium. Serum normalized ionized calcium(nCa2+) concentration was measured in patients receiving resection of brain tumor(Group l) and hepatic lobectomy(Group 2) before and after transfusion The results were as follows; l) nCa2+ concentration decreased from 1.08+/-0.08 mmol/L at baseline to 0.98+/-0.10 mmol/L(p< 0.05) at 10 min after transfusion in Group l. 2) nCa2+ concentration decreased from 1.13+/-0.05 mmol/L at baseline to 0.84+/-0.08 mmol/L(p< 0.01) at 10min and to 0.87+/-0.11 mmol/L(p<0.05) at 2hr after transfusion in Group 2. 3) nCa2+ concentration at 10 min and 2hr after transfusion in Group 2 were significantly lower than those in Group l(p<0.05). nCa2+ concentration decreased significantly after transfusion and didnt returned to baseline at 2hr after transfusion during hepatic lobectomy. We conclude that it is essential to measure ionized calcium(Ca2+) concentration directly and at frequent interval during transfusion in hepatic surgery and we can prevent or treat severe hypocalcemia and cardiovascular depression with measured serum Ca2+.
