A Case of Allopurinol-Induced Fixed Drug Eruption Confirmed With a Lymphocyte Transformation Test.
10.4168/aair.2012.4.5.309
- Author:
Min Hye KIM
1
;
Eun Jin SHIM
;
Jae Woo JUNG
;
Seong Wook SOHN
;
Hye Ryun KANG
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. helenmed@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Allopurinol;
fixed drug eruption;
lymphocyte transformation test
- MeSH:
Allopurinol;
Drug Eruptions;
Drug Hypersensitivity;
Humans;
Lymphocyte Activation;
Lymphocytes
- From:Allergy, Asthma & Immunology Research
2012;4(5):309-310
- CountryRepublic of Korea
- Language:English
-
Abstract:
Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is reported to be rarely positive in patients with FDE. In the current case, we performed an LTT and successfully confirmed allopurinol as the offending drug. This case report suggests that an LTT should be an optional diagnostic tool for FDE or delayed reaction due to allopurinol.
